May 30 2019
A group including Professor Eisaku Kondo and Assistant Professor Hidekazu Iioka (Division of Molecular and Cellular Pathology, Niigata University Graduate School of Medical and Dental Sciences) found that Crumbs3 (Crb3) which is essential to embryogenesis, is deeply involved in metastasis of colorectal cancer (CRC) as an invasion initiator. Detailed analyses of its mechanism will contribute to establishing preventive therapeutics for CRC metastasis.
Title: Crumbs3 is a critical factor that regulates invasion and metastasis of colon adenocarcinoma via the specific interaction with FGFR1
Journal: International Journal of Cancer
Authors: Hidekazu Iioka, Ken Saito, Masakiyo Sakaguchi, Taro Tachibana, Keiichi Homma, Eisaku Kondo
DOI: 10.1002/ijc.32336
A Gene Locus Controlling Zinc Content in Common Beans Identified: Nutritional Improvement Expected Through The Molecular Breeding Of Zinc-Enrichmed Varieties
Elevated cdc42 activity is a key initiation event leading to proteinuria. -Regulation of cdc42 activity could be a promising therapy for nephrotic syndrome.-
Temozolomide and radiation treatment lead to dramatic tumor shrinkage and improvement of hearing in an adult brainstem glioma patient with a rare IDH2 mutation