Identification of a new gene that causes metastasis of colon cancer.
May 30, 2019
A group including Professor Eisaku Kondo and Assistant Professor Hidekazu Iioka (Division of Molecular and Cellular Pathology, Niigata University Graduate School of Medical and Dental Sciences) found that Crumbs3 (Crb3) which is essential to embryogenesis, is deeply involved in metastasis of colorectal cancer (CRC) as an invasion initiator. Detailed analyses of its mechanism will contribute to establishing preventive therapeutics for CRC metastasis.
Publication Details
Title: Crumbs3 is a critical factor that regulates invasion and metastasis of colon adenocarcinoma via the specific interaction with FGFR1
Journal: International Journal of Cancer
Authors: Hidekazu Iioka, Ken Saito, Masakiyo Sakaguchi, Taro Tachibana, Keiichi Homma, Eisaku Kondo
DOI: 10.1002/ijc.32336
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