May 01 2020

Graduate student Rie Habuka, Professor Akihiko Saitoh, and colleagues at the Division of Pediatrics, Niigata University Graduate School of Medical and Dental Sciences in collaboration with the Division of Microbiology and Infectious Diseases (Professor Yutaka Terao and colleagues) and the Division of Bioinformatics (Associate Professor Shujiro Okuda and colleagues), Niigata University Graduate School of Medical and Dental Sciences conducted a study in which they compared and elucidated the differences between the immune responses of neonates and infants infected with parechovirus-A3 and enteroviruses. The results of this research may be useful for the treatment preventing serious conditions of these two infections. Furthermore, it may provide important clues to better understand why the currently prevailing COVID-19 infection causes serious clinical manifestations in infants.

Publication Details

Title: Innate Immune Responses in Serum and Cerebrospinal Fluid From Neonates and Infants Infected With Parechovirus-A3 or Enteroviruses

Journal: The Journal of Infectious Diseases

Authors: Rie Habuka, Yuta Aizawa, Ryohei Izumita, Hisanori Domon, Yutaka Terao, Hayato Takihara, Shujiro Okuda, Akihiko Saitoh

DOI: 10.1093/infdis/jiaa131