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  4. Notable Research in Articles

Notable Research in Articles

In many academic fields, research results are first published in academic journals. Here, among the articles included in the Web of Science bibliographic database of Clarivate Analytics, we will show the number of such articles published by researchers at Niigata University and those that are particularly referred to worldwide in each field.

1. Total number of articles at Niigata University

The total number of articles and reviews by researchers at Niigata University that have been published in the last five years are shown for each year.

Filter Summary:
Dataset: InCites Dataset + ESCI
Schema: Web of Science
Domestic/International Collaboration: All
Time Period: [2018, 2022]
Include Early Access documents: true
Document Type: [Article, Review]
Organization Name: [Niigata University]

2. Highly cited articles (Top 1% )

Multiple ways are available to evaluate whether an academic publication is rated high worldwide. One is to determine based on citations. Excellent publications will be cited in the publications that follow, resulting in a high number of citations. In this method, we set the group by year and field, ranking each publication based on the number of citations in descending order, measuring where in the top percentage of the group the publication is placed. Here, we will show introduce articles whose primary authors are researchers at Niigata University. The publications are from in the last five years and from those highly evaluated the most often referred to worldwide (top 1% by citations), and are cited in the top one percent for each of the 22 research fields (ESI fields) established by the Web of Science.


Takahiro Tsuzuno, D.D.S., Ph.D.(Specially Appointed Assistant Professor), Naoki Takahashi, D.D.S., Ph.D.(Associate Professor)
Graduate School of Medical and Dental Sciences Oral Life Science Oral Biological Science, University Medical and Dental Hospital Advanced Clinical Research Center
Web site of Lab

Ingestion of Porphyromonas gingivalis exacerbates colitis via intestinal epithelial barrier disruption in mice

Year2021 Vol.56 Issue2 Pages 275-288
DOI: https://doi.org/10.1111/jre.12816

Periodontitis has negative effects on several systemic diseases. In this study, we examined the effects of periodontopathogenic bacteria on intestinal diseases. We demonstrated that P. gingivalis, a major bacterium causing periodontitis, aggravates intestinal inflammation in vivo. As a mechanism, we proposed that a specific protease produced by P. gingivalis exacerbates inflammation by disrupting the intestinal epithelial barrier function

First authors : Takahiro Tsuzuno [1] [2]

Corresponding authors : Naoki Takahashi [2], Kazuhisa Yamazaki [1]

Affiliations of corresponding authors :[1] Niigata Univ, Fac Dent, Dept Oral Biol Sci, Div Periodontol, [2] Niigata Univ, Grad Sch Med & Dent Sci, Div Oral Sci Hlth Promot, Res Unit Oral Syst Connect

Authors :Takahiro Tsuzuno, Naoki Takahashi, Miki Yamada-Hara, Mai Yokoji-Takeuchi, Benso Sulijaya, Yukari Aoki-Nonaka, Aoi Matsugishi, Kyoko Katakura, Koichi Tabeta, Kazuhisa Yamazaki


Manako Yamaguchi, M.D., Ph.D. (Specially Appointed Assistant Professor), Kosuke Yoshihara, M.D., Ph.D. (Professor)
Graduate School of Medical and Dental Sciences Molecular and Cellular Medicine Molecular, Obstetrics and Gynecology
Web site of Lab

Three-dimensional understanding of the morphological complexity of the human uterine endometrium

Year2021 Vol.24 Issue4 Pages 102258
DOI: 10.1016/j.isci.2021.102258

While the human endometrium is essential for implantation of a fertilized egg, it is also the origin of the endometriosis and endometrial cancer. In this study, we succeed to visualize the real three-dimensional (3D) structure of the human endometrium using tissue-clearing and 3D imaging technology. Although each individual gland was thought to be independent for many years, we discovered that the endometrial glands form a network structure (Rhizome) in the stratum basalis of the human endometrium. Understanding the true 3D structure of the human endometrial glands will lead to the elucidation of the mechanisms of menstruation and implantation, and the pathogenesis of endometriosis and endometrial cancer.

First authors : Manako Yamaguchi [1]

Corresponding authors : Kosuke Yoshihara [1],Kazuki Tainaka [2][3]

Affiliations of corresponding authors: [1] Niigata Univ, Dept Obstet & Gynecol, Grad Sch Med & Dent Sci, [2] Niigata Univ, Brain Res Inst, Dept Syst Pathol Neurol Disorders, [3] RIKEN Ctr Biosyst Dynam Res, Lab Synthet Biol, Suita

Authors :Manako Yamaguchi, Kosuke Yoshihara, Kazuaki Suda, Hirofumi Nakaoka, Nozomi Yachida, Haruka Ueda, Kentaro Sugino, Yutaro Mori, Kaoru Yamawaki, Ryo Tamura, Tatsuya Ishiguro, Teiichi Motoyama, Yu Watanabe, Shujiro Okuda, Kazuki Tainaka, Takayuki Enomoto