Notable Research in Articles

In many academic fields, research results are first published in academic journals. Here, among the articles included in the Web of Science bibliographic database of Clarivate Analytics, we will show the number of such articles published by researchers at Niigata University and those that are particularly referred to worldwide in each field.

1. Total number of articles at Niigata University

The total number of articles and reviews by researchers at Niigata University that have been published in the last five years are shown for each year.

Filter Summary:
Dataset: InCites Dataset + ESCI
Schema: Essential Science Indicators

Time Period: [2014, 2018]
Document Type: [Article, Review]
Organization Name: [Niigata University]
Exported date 2019-12-10.
InCites dataset updated Nov 26, 2019. Includes Web of Science content indexed through Oct 31, 2019.

2. Highly cited articles (Top 1% )

Multiple ways are available to evaluate whether an academic publication is rated high worldwide. One is to determine based on citations. Excellent publications will be cited in the publications that follow, resulting in a high number of citations. In this method, we set the group by year and field, ranking each publication based on the number of citations in descending order, measuring where in the top percentage of the group the publication is placed. Here, we will show introduce articles whose primary authors are researchers at Niigata University. The publications are from in the last five years and from those highly evaluated the most often referred to worldwide (top 1% by citations), and are cited in the top one percent for each of the 22 research fields (ESI fields) established by the Web of Science.

BIOCHEMISTRY & MOLECULAR BIOLOGY

Dr. Shujiro Okuda (Associate Prof.)
Graduate School of Medical and Dental Sciences Research professor, Institute for Research Promotion
Web site of Lab

jPOSTrepo: an international standard data repository for proteomes

NUCLEIC ACIDS RESEARCH
Year 2017 Vol. 45 Issue D1 Pages D1107-D1111
DOI: 10.1093/nar/gkw1080

Protein sequence data, as well as gene sequences, are becoming to be shared to all researchers around the world. The jPOST repository (jPOSTrepo) was developed as the first international standard proteome data repository in the Asia-Oceania region. The jPOST repository plays a role as a reusable data sharing platform for proteome data studied all over the world.

Corresponding authors : Okuda, Shujiro [1], Yasushi Ishihama [2]

Affiliations of corresponding authors : [1] Niigata Univ, Grad Sch Med & Dent Sci [2] Kyoto Univ, Grad Sch Pharmaceut Sci

Authors : Shujiro Okuda, Yu Watanabe, Yuki Moriya, Shin Kawano, Tadashi Yamamoto, Masaki Matsumoto, Tomoyo Takami, Daiki Kobayashi, Norie Araki, Akiyasu C. Yoshizawa, Tsuyoshi Tabata, Naoyuki Sugiyama, Susumu Goto and Yasushi Ishihama

CELL BIOLOGY

Dr. NAKATSU, Fubito (Associate Professor)
Graduate School of Medical and Dental Sciences Division of Molecular and Cellular Biology
Web site of Lab

PI4P/phosphatidylserine countertransport at ORP5-and ORP8-mediated ER-plasma membrane contacts

SCIENCE
Year 2015 Vol. 349 Issue 6246 Pages  428-432
DOI: 10.1126/science.aab1370

Lipid transfer between cell membrane bilayers at contacts between the endoplasmic reticulum (ER) and other membranes help to maintain membrane lipid homeostasis. We found that two similar ER integral membrane proteins, oxysterol-binding protein (OSBP)-related protein 5 (ORP5) and ORP8, tethered the ER to the plasma membrane (PM) via the interaction of their pleckstrin homology domains with phosphatidylinositol 4-phosphate (PI4P) in this membrane. Their OSBP-related domains (ORDs) harbored either PI4P or phosphatidylserine (PS) and exchanged these lipids between bilayers. Gain- and loss-of-function experiments showed that ORP5 and ORP8 could mediate PI4P/PS countertransport between the ER and the PM, thus delivering PI4P to the ER-localized PI4P phosphatase Sac1 for degradation and PS from the ER to the PM. This exchange helps to control plasma membrane PI4P levels and selectively enrich PS in the PM.

Corresponding authors : Nakatsu, Fubito [1,2,3], De Camilli, Pietro [2,3]

Affiliations of corresponding authors: [1] Niigata Univ, Grad Sch Med & Dent Sci, Dept Neurochem & Mol Cell Biol [2] Yale Univ, Sch Med, Dept Cell Biol, Howard Hughes Med Inst, Kavli Inst Neurosci [3] Yale Univ, Sch Med, Program Cellular Neurosci Neurodegenerat & Repair

Authors : Jeeyun Chung, Federico Torta, Kaori Masai, Louise Lucast, Heather Czapla, Lukas B. Tanner, Pradeep Narayanaswamy, Markus R. Wenk, Fubito Nakatsu, Pietro De Camilli